The University of Wisconsin Department of Pathology offers a ten-week internship for up to four students following their first year of medical school. This is designed to provide exposure to modern pathology practice while furthering medical education. Participants will rotate through eight services during the summer. The principal requirements of the students are enthusiasm and attendance. The typical workday begins at 8:00 a.m. and ends between 4:00 and 5:00 p.m. Weekends are open. Activities for the ten weeks are outlined below. A brief description of the rotations follows.
Autopsy Service (Two Weeks)
Students will begin on the autopsy service. Approximately 500-550 post mortem examinations are performed here annually. These include a wide array of medical, pediatric, and forensic cases. The essential goal of an autopsy is to identify or confirm cause of death. Individuals will be observing procedures at first, however, assisting with gross dissection is allowed as time progresses. Fellows are expected to follow up with microscopy and brain cutting on their cases. Additional involvement during subsequent rotations is encouraged, time permitting.
Clinical Chemistry (One Week)
Clinical chemistry analyzes blood and body fluids for electrolytes, proteins, enzymes, and a wide array of metabolites. Therapeutic drug levels and toxicology are also performed in this laboratory. Most methods of analysis utilize very sophisticated, automated technologies. Examples include spectrophotometry, mass spectrometry, and chromatography. Many assays are tailored to the specific substance being measured. Students will tour the laboratory as an overview and have opportunity to explore individual interests.
Hematopathology (One Week)
The hematopathology service evaluates the cellular elements of blood, bone marrow, and lymph nodes. Specimens evaluated are from patients with all varieties of hematologic disorders including leukemias, lymphomas, and any type of anemia. Interpretation of many cases requires additional laboratory data such as that provided by the chemistry lab. The hematopathologist also utilizes flow cytometry to assist in diagnosing various malignancies. This technology identifies cell surface antigens by a state-of-the-art-automated process.
Clinical Microbiology (One Week)
The clinical microbiology laboratory examines a wide variety of patient materials for the presence of infectious agents or an immune response to them. Specimens include throat, sputum, stool, blood, skin and soft tissue and miscellaneous fluids. Bacterial, fungal, parasitic or viral agents may be sought by microscopy, culture, antigen detection, nucleic acid detection or antibody response. Antimicrobial resistance is determined to help guide therapy.
Transfusion Medicine (One Week)
Transfusion medicine concerns the utilization of blood and blood products. This is an integral part of hospital based medical and surgical services. The blood bank collects, processes, stores and distributes such products. Activities in this lab include cross-matching patients with donors in addition to investigating adverse patient reactions to infused products. Students will also gain insight into the principles and practice of screening blood products for infectious agents.
Cytology / State Lab (One Week)
The cytology division analyzes cell “smears” rather than tissue sections. This adds an extra degree of challenge with interpretation since the histological architecture is not present. The bulk of cases are gynecologic (Pap smears). Additional cases reviewed include peritoneal and pleural fluids, cerebrospinal fluid, and urine. This department also interprets fine needle aspirates. The variety of aspirates examined is diverse, however, most are from breast, thyroid, lymphoid and soft tissues.
Surgical Pathology (Two Weeks)
Surgical pathology entails making diagnoses on surgically removed patient specimens. This is one of the busiest laboratory services at the UW. Specimens received come from virtually every anatomic site in the human body. Tissues are examined grossly and sectioned, usually on the day of surgery. The following day, histologic slides are evaluated and final diagnoses reported. Additional activities include intraoperative consultations, utilization of special histologic techniques for challenging cases, and numerous clinicopathologic interdepartmental conferences.
Molecular Pathology (One Week)
Increasing knowledge of the molecular basis of disease and advances in technology for analyzing nucleic acids and gene products are changing pathology practice. The explosion of molecular information regarding the inherited susceptibility to disease, the detection of disease prior to any clinical presentation, and the ability to assess prognosis and efficacy of therapy are each an important aspect in this transformation. In the Molecular Pathology rotation, the Angevine fellows receive a practical experience in nucleic acid based testing and how these analyses can be applied and are assimilated with other laboratory and clinical information in the advancement of patient care.
“Being a recipient of the Angevine Fellowship in Pathology has inspired my career and enriched my clinical and academic work. My experience as an Angevine fellow nurtured an interest in pathology, leading me to seek a career where I could use training in pathology to benefit my patients at the bedside. My work as a Mohs surgeon allows me to bring the benefit of real-time histologic analysis to the patient undergoing resection of skin cancer in the outpatient setting. I am able to couple my skills as a clinician and surgeon with my skills as a pathologist in my work as a Mohs surgeon. The technique is tissue sparing and is the gold standard treatment for skin cancer, providing the highest possible cure rates. This work is so rewarding, and I am so fortunate to see how my interest and experience in pathology, supported and nurtured by the Angevine fellowship, makes a difference in the lives of cancer patients every day. I am forever grateful for this opportunity and for the vision and generosity of the Angevine family.”
- Juliet Aylward, MD, FAAD, FACMS
Clinical Professor of Dermatology
Nelson M. Hagan Class of 1929 Chair
Section Chief, Mohs and Dermatologic Surgery
Department of Dermatology
University of Wisconsin School of Medicine and Public Health
May 30th – August 4th, 2023
Satisfactory completion of first year of medical school (UW-Madison students strongly preferred).
Fellows are paid a stipend of $3,500.
Jamie E. Kallan, MD
Director of Angevine Fellowship
C/O Sara Gross, Angevine Fellowship Director
University of Wisconsin Hospital & Clinics
600 Highland Ave, L5/173
Madison, WI 53792